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[Cytomegalovirus hepatitis].

T Laskus1, E Lupa, J Cianciara

  • 1Zakładu Immunopatologii Chorób Zakaźnych i Pasozytniczych.

Polskie Archiwum Medycyny Wewnetrznej
|January 1, 1991
PubMed
Summary
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Cytomegalovirus (CMV) is a rare cause of acute hepatitis, diagnosed in 0.9% of hospitalized patients. While the disease course is similar to other hepatitis types, cholestasis is common and biochemical markers normalize within weeks.

Area of Science:

  • Hepatology
  • Virology
  • Infectious Diseases

Context:

  • Acute hepatitis is a significant cause of hospitalization.
  • Cytomegalovirus (CMV) is a common virus with diverse clinical manifestations.
  • Hepatitis A, B, and non-A, non-B represent common etiologies of viral hepatitis.

Purpose:

  • To determine the incidence and clinical characteristics of cytomegalovirus (CMV) infection presenting as acute hepatitis.
  • To compare the clinical course and biochemical profile of CMV hepatitis with other viral hepatitis types.

Summary:

  • Cytomegalovirus (CMV) infection was diagnosed in 5 (0.9%) of 530 hospitalized patients with acute hepatitis.
  • Two cases of CMV hepatitis were attributed to blood transfusion.
  • The clinical presentation of CMV hepatitis showed common manifestations of cholestasis, with biochemical abnormalities resolving within weeks.

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  • The disease course did not significantly differ from hepatitis A, B, or non-A, non-B.

    • Impact:

    • Cytomegalovirus (CMV) is identified as a rare but potential cause of clinically apparent hepatitis.
    • The findings highlight the cholestatic nature often associated with CMV hepatitis.
    • This study contributes to understanding the spectrum of CMV disease and its implications in immunocompetent individuals.