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Published on: September 8, 2023
Post-mortem magnetic resonance imaging provides the diagnosis following aortic rupture in an infant with treated
Andrew M Taylor1, Rod Jones, Graham Derrick
1Cardiothoracic Unit, and Department of Radiology, Institute of Child Health & Great Ormond Street Hospital for Children, London, United Kingdom. a.taylor@ich.ucl.ac.uk
Insights
Post-mortem MRI successfully diagnosed aortic rupture in a child, even when conventional autopsy was declined. This imaging technique offers a valuable alternative for determining cause of death in pediatric cardiovascular cases.
Area of Science:
- Pediatric cardiovascular pathology
- Medical imaging
- Forensic pathology
Background:
- Conventional pediatric autopsies are declining in the UK.
- Congenital cardiac malformations are often diagnosed using Magnetic Resonance Imaging (MRI) during life.
- Structural, rather than pathological, factors are crucial in pediatric cardiovascular disease deaths.
Observation:
- A case report details a patient with a history of surgical repair for aortic interruption.
- Parents declined a conventional histopathological autopsy.
- Post-mortem Magnetic Resonance Imaging (pmMRI) was approved.
Findings:
- pmMRI successfully diagnosed aortic rupture in the patient.
- This non-invasive imaging confirmed the cause of death.
- pmMRI provided diagnostic information without the need for traditional autopsy.
Implications:
- pmMRI is a viable alternative to conventional autopsy for pediatric cardiovascular deaths.
- This imaging modality can aid in establishing cause of death when autopsies are refused.
- Advances in pmMRI can improve diagnostic accuracy in pediatric forensic cases.
Abstract:
In the United Kingdom, there has been a steady decline in the number of conventional autopsies performed in children. For cardiovascular disease, structural and not pathological considerations are often more important in defining the cause of death. Magnetic resonance imaging is now often used in the assessment of congenital cardiac malformations during life. In this case report, we demonstrate how post-mortem magnetic resonance imaging was able to establish the diagnosis of aortic rupture in a patient who had undergone surgical repair of aortic interruption. In this patient, the parents had declined conventional histopathological autopsy, but were happy to consent to magnetic resonance post-mortem assessment.
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