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Updated: Aug 11, 2026

Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles
Published on: November 10, 2017
Other than potency, are all statins the same?
Nicola Abate1, Manisha Chandalia
1Department of Internal Medicine, UT Southwestern Medical Center, 6011 Harry Hines Boulevard, Dallas, TX 75390-9169, USA. Nicola.abate@utsouthwestern.edu
Abstract:
Statins have been shown to interact with metabolic pathways that potentially affect physiologic functions beyond cholesterol balance. We may broadly categorize non-lipid effects of statins as clinically favorable or clinically detrimental. Whether non-lipid effects of statins are of clinical significance and whether there are differences in non-lipid effects among statins remain points of major current controversy. This review evaluates the available information on potential differences among statins in non-lipid effects.
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