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Updated: Aug 11, 2026
A Murine Model of a Burn Wound Reconstructed with an Allogeneic Skin Graft
Published on: August 8, 2020
Eyelid reconstruction with acellular human dermal allograft after chemical and thermal burns
Chen Jiaqi1, Wang Zheng, Gu Jianjun
1Zhongshan Ophthalmic Center, Department of Plastic, Sun Yat-sen University, 54 Xianlienan Road, Guangzhou 510060, PR China.
Objective:
To evaluate the efficacy of eyelid reconstruction with acellular dermal allograft in patients with eyelid defect after chemical and thermal burns.
Method:
Eyelid reconstruction was performed in 15 eyelids of 13 patients during the period of June 2001-October 2004 by a single senior surgeon (Chen). Among them five patients had thermal burns, and eight patients had chemical burns. The acellular dermal allograft was used as a tarsus substitute that was sutured into the place between the levator aponeurosis in upper lid or retractor in lower eyelid and the remaining tarsus.
Results:
After a mean follow-up of 9 months, satisfactory function and cosmesis were obtained. No implant rejection or severe complications were observed.
Conclusion:
Acellular dermal allograft may be used safely as a posterior lamellar spacer graft after chemical and thermal burns; the allograft appears to be biocompatible and does not aggravate the inflammation in the injured eyelid.
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