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Updated: May 12, 2026

Interview: Glycolipid Antigen Presentation by CD1d and the Therapeutic Potential of NKT cell Activation
Published on: January 1, 2008
1. Overview of the human immune response
1University of Alabama at Birmingham, 845 19th Street South, Birmingham, AL 35294, USA. dchaplin@uab.edu
Abstract:
The human immune system mobilizes a broad repertoire of innate and adaptive responses to protect against the universe of pathogens it encounters. Central to these protective responses are its mechanisms to distinguish self from nonself. This overview describes the major mechanisms used by the immune system to respond to invading microbes and identifies settings in which disturbed immune function exacerbates tissue injury.
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