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Updated: Jun 19, 2026

Absorption of Nasal and Bronchial Fluids: Precision Sampling of the Human Respiratory Mucosa and Laboratory Processing of Samples
Published on: January 21, 2018
7. Control of allergic airway inflammation through immunomodulation
David B Corry1, Farrah Kheradmand
1Departments of Medicine and Immunology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA. dcorry@bcm.tmc.edu
Abstract:
Among the asthma clinical trials published over the last several years, a unique subset has focused on novel means for inhibiting the airway inflammation that is believed to cause airway obstruction in many patients. Such interventions, broadly considered here as immune-modifying or immunomodulatory therapies, include several new drugs (omalizumab, suplatast tosilate, anti-cytokine antibodies, soluble receptors, and recombinant cytokines) and bacterial extracts. In this chapter we review the major findings with these clinical trials and indicate which have changed the management of asthma, which have not, and those that deserve further study.
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