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Updated: Aug 11, 2026

Mucin Agarose Gel Electrophoresis: Western Blotting for High-molecular-weight Glycoproteins
Published on: June 14, 2016
Regulation of mucin genes in chronic inflammatory airway diseases
Judith A Voynow1, Sandra J Gendler, Mary C Rose
1Department of Pediatrics, Duke University Medical Center, Durham, NC 27710, USA. voyno001@mc.duke.edu
Abstract:
In this review, we summarize work over the past 15 years on mucin gene expression and regulation in the lung, as well as how mucin gene expression is altered in chronic lung diseases. This field owes a great debt to Carol Basbaum for her pioneering work in dissecting signaling pathways regulating mucin gene expression and for her tremendous energy in promoting the importance of understanding the basic pathogenic mechanisms that drive mucus overproduction in cystic fibrosis, chronic obstructive pulmonary disease, and asthma.
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