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Published on: August 1, 2019
A prospective study comparing oral sodium phosphate solution to a bowel cleansing preparation with nutrition food
Mohammad F El-Baba1, Mary Padilla, Carmela Houston
1Department of Pediatrics, Children's Hospital of Michigan, Detroit, MI, USA.
Insights
A prepackaged diet kit with magnesium citrate/bisacodyl laxative offers superior colon cleansing for pediatric colonoscopy compared to clear liquids and sodium phosphate. This regimen improves visualization and reduces side effects in children undergoing the procedure.
Area of Science:
- Pediatric Gastroenterology
- Endoscopic Procedures
- Gastrointestinal Motility
Background:
- Pediatric bowel preparation is crucial for effective colonoscopy.
- Poor patient compliance with traditional regimens leads to inadequate colon visualization.
- Novel approaches are needed to improve bowel prep in children.
Purpose of the Study:
- To compare the safety, efficacy, and patient acceptance of two bowel preparation regimens in children undergoing colonoscopy.
- To evaluate a prepackaged diet kit with magnesium citrate/bisacodyl versus a clear liquid diet with sodium phosphate solution.
Main Methods:
- Children were randomized to receive either a prepackaged diet kit with magnesium citrate/bisacodyl or clear liquids with sodium phosphate.
- Patient and parent questionnaires assessed regimen acceptance.
- Endoscopists, blinded to the preparation type, rated bowel cleansing quality.
Main Results:
- The prepackaged diet kit group showed significantly superior colon cleansing and less retained feces.
- The incidence of reported side effects was lower in the prepackaged diet kit group (83.3%) compared to the clear liquid group (100%).
- Compliance and tolerance were comparable between the two groups.
Conclusions:
- The prepackaged diet kit with magnesium citrate/bisacodyl resulted in superior colon cleansing.
- Both regimens were comparable in colon visualization adequacy, tolerance, and compliance.
- This regimen may be a more effective option for pediatric bowel preparation.
Objective:
The inability of children to comply with bowel preparation regimens can result in inadequate visualization of the colon. This study compares the safety, efficacy, and patient acceptance of a prepackaged diet kit plus a magnesium citrate/bisacodyl bowel cleansing regimen with a clear liquid diet and sodium phosphate solution regimen in children undergoing colonoscopy.
Methods:
Children scheduled for a diagnostic colonoscopy, were randomly assigned to receive a prepackaged diet kit and a magnesium citrate/bisacodyl laxative (group 1), or clear liquids and sodium phosphate solution (group 2). The patients and their parents completed a questionnaire to evaluate acceptance of their assigned regimen before colonoscopy. The endoscopists, blinded to the type of bowel preparation, rated bowel cleansing.
Results:
Sixty two children (28 males, 34 females) with mean age 12.5 years participated. Thirty six and 26 patients were in groups 1 and 2 respectively. Overall cleansing was rated significantly superior in group 1 compared to group 2 as was amount of retained feces (P = .013 for both). The overall frequency of reported side-effects was lower in group 1 than (83.3%, 30/36) than in group 2 (100.0%, 26/26) (P = 0.03). The preparations were otherwise equivalent in regards to compliance and patient tolerance.
Conclusions:
Although both regimens were comparable in adequacy of colon visualization, preparation tolerance, side effects and compliance profile in this pilot study, the prepackaged diet kit with magnesium citrate/bisacodyl laxative resulted in superior colon cleansing.
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