Related Experiment Video
Updated: Aug 11, 2026

04:41
Treatment with Locking Intramedullary Nailing for Intertrochanteric Fracture of the Femur Utilizing a New Awl with a Distal Positioner
Published on: June 6, 2025
Computer-assisted technique versus intramedullary and extramedullary alignment systems in total knee replacement: a
Norberto Confalonieri1, Alfonso Manzotti, Chris Pullen
11st Orthopaedic Department, Centro Traumatologico ed Ortopedico, Milan, Italy.
Acta Orthopaedica Belgica
|February 8, 2006
Summary
Accurate alignment in total knee replacement (TKR) is crucial. While mean alignment angles were similar across computer, intramedullary, and extramedullary systems, the extramedullary group showed more malalignments.
Area of Science:
- Orthopedic Surgery
- Biomedical Engineering
- Radiology
Background:
- Knee replacement malalignment is linked to implant failure and reduced function.
- Precise component positioning is vital for successful total knee replacement (TKR).
Purpose of the Study:
- To compare radiological alignment outcomes of three different total knee replacement (TKR) alignment techniques.
- To evaluate the accuracy of computer-based, intramedullary, and extramedullary alignment systems in TKR.
Main Methods:
- Retrospective comparison of three TKR series (n=38 computer, n=40 intramedullary, n=37 extramedullary).
- Radiological assessment of frontal-femoral-component (FFC) angle, frontal-tibial-component (FTC) angle, hip-knee-ankle (HKA) angle, and tibial slope at 12 months post-op.
- Statistical analysis of alignment parameters across the three groups.
Main Results:
- No statistically significant differences in mean FFC, FTC, HKA angles, or tibial slope between the groups.
- A higher percentage of abnormal FFC and HKA angles were observed in the extramedullary alignment group.
- All computer-aligned TKRs achieved ideal HKA and tibial slope within 4 degrees.
Conclusions:
- While mean alignment is comparable, extramedullary alignment may lead to a higher rate of outliers.
- Computer-based alignment systems demonstrate high precision in achieving target TKR alignment parameters.