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Palatal neurofibroma associated with localized periodontitis
Charles A Powell1, Corey M Stanley, Sharon R Bannister
1U.S. Air Force Periodontics Residency, Wilford Hall Medical Center, Lackland Air Force Base, TX 78236, USA. charles.powell@lackland.af.mil
Journal of Periodontology
|February 8, 2006
Summary
Intraoral neurofibromas in patients with Neurofibromatosis type 1 (NF1) can mimic periodontal disease, causing significant alveolar bone destruction. Early diagnosis and medical referral are crucial for managing these rare but serious oral manifestations.
Area of Science:
- Oral pathology
- Dermatology
- Radiology
Background:
- Neurofibromatosis type 1 (NF1) is a common genetic disorder.
- Intraoral manifestations of NF1 are frequent but often overlooked.
- Palatal neurofibromas can be misdiagnosed as periodontitis due to similar clinical signs like periodontal pockets.
Observation:
- A 40-year-old female with a history of neurofibroma excision and NF1 diagnosis presented with symptoms of advanced periodontitis.
- Periodontal probing revealed deep pockets (6-9 mm) around maxillary teeth #14 and #15.
- Radiographs showed a radiolucent lesion near tooth #13 and significant bone loss around tooth #15.
Findings:
- Histopathologic examination confirmed the presence of a neurofibroma.
- The oral lesion demonstrated extensive alveolar bone destruction.
- The radiographic and clinical findings mimicked severe periodontitis.
Implications:
- Neurofibromas can lead to substantial destruction of the alveolar bone, presenting a diagnostic challenge.
- Accurate diagnosis of oral neurofibromas is essential due to potential systemic and genetic implications.
- Prompt medical referral is necessary for patients diagnosed with neurofibromas to ensure comprehensive care.
