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Updated: Aug 11, 2026

Models of Murine Vaginal Colonization by Anaerobically Grown Bacteria
Published on: May 25, 2022
Pregnancy outcome after early detection of bacterial vaginosis
Brunella Guerra1, Tullio Ghi, Simona Quarta
1Department of Obstetrics and Gynecology, Policlinico S.Orsola-Malpighi, Alma Mater Studiorum-University of Bologna, Italy.
Objective:
To assess if detecting bacterial vaginosis either in early pregnancy or at midtrimester may predict adverse pregnancy outcome in women at risk for preterm delivery.
Study Design:
242 pregnant women with a previous preterm delivery were evaluated for bacterial vaginosis either in the first trimester (prior to 10+0 weeks) or in the second one (24-26 weeks). Adverse outcome was intended as miscarriage (< or =25 weeks), or premature delivery (< or =36+6).
Results:
The risk of adverse pregnancy outcome was significantly increased in women diagnosed at first trimester with bacterial vaginosis (OR: 4.56; 95% CI: 2.54-8.93); the same finding at midtrimester did not increase significantly the risk of preterm delivery.
Conclusions:
Early screening for bacterial vaginosis in pregnant women who experienced a preterm delivery may help in predicting the risk of adverse outcome.
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