Related Experiment Video
Updated: Aug 11, 2026

Development of a Hepatitis B Virus Reporter System to Monitor the Early Stages of the Replication Cycle
Published on: February 1, 2017
Software and expert system for the management of chronic hepatitis B
Riccardo Neirotti1, Filippo Oliveri, Maurizia R Brunetto
1Direzione Scientifica, Fondazione IRCCS, Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milano, Italy.
Abstract:
Whereas the doubling time of overall biomedical knowledge bases has been estimated at about 19 years, the body of indexed information related to HBV has doubled in the last 8 years; the one related to HBV and antivirals has doubled in the last 5 years and the one related to Interferon and contraindications has doubled in less than 48 months. In Hepatology, as well as in other fast changing areas of medicine, the demand that clinical decision should always be based on the best verified knowledge available, is becoming more and more difficult to comply with. The Italian network of competence for hepatic diseases (Liver Unit Networks Association or LUNA) was established in 2003 with the patronage of the Italian Ministry of Health, with the primary goal of promoting advanced clinical research and real-time information exchange among the participating centres, facilitating knowledge sharing and identification of best practices. The ICT infrastructure designed for this purpose includes four sets of online accessible software tools:
Related Concept Videos
Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test
Hepatitis
Chronic Pancreatitis II: Collaborative Care
Assessment:
Viral Hepatitis I: Introduction
Cirrhosis I: Introduction
Diseases of the Liver and Gallbladder
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not related to...
