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Prognostic value of quantitative analysis of WT1 gene transcripts in adult acute lymphoblastic leukemia
Haematologica
|February 8, 2006
Abstract:
We quantified Wilm's tumor gene (WT1) using a real time quantitative polymerase chain reaction in 20 adult patients with acute lymphoblastic leukemia at presentation. A WT1 level greater than 906 (median value for the whole series) was a significant predictor of a poor disease-free and overall survival in uni- and multivariate analyses.