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Updated: Aug 11, 2026

Detection of Invasive Pulmonary Aspergillosis in Haematological Malignancy Patients by using Lateral-flow Technology
Published on: March 22, 2012
Pneumonia with marked pleural effusion caused by Aspergillus infection
Fumi Miyake1, Tetsushi Yoshikawa, Ayano Fujita
1Department of Pediatrics, Fujita Health University School of Medicine, Toyoake, Aichi, Japan.
Abstract:
We present a case of pneumonia with marked pleural effusion caused by Aspergillus infection in a 2-year-old Japanese girl with Down's syndrome. The patient was previously diagnosed with acute myeloid leukemia, developing the pneumonia during induction treatment. Although no pathogens could be isolated from any clinical specimens, 135,000 copies/mL of Aspergillus DNA were detected in the pleural fluid using real time polymerase chain reaction. The copy numbers of DNA decreased rapidly after appropriate antifungal treatment.
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