Defects in cardiomyocyte function: role of beta-adrenergic receptor dysfunction.

C Perrino1, G Esposito, H A Rockman

  • 1Department of Medicine, Cell Biology and Molecular Genetics, Duke University Medical Center, Durham, NC, USA.

Panminerva Medica
|February 8, 2006
PubMed
Summary

This review examines the controversial role of beta-adrenergic receptor (betaAR) signaling in heart failure. It explores how betaAR dysfunction impacts failing heart cells and discusses strategies to normalize signaling for improved contractility.

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