[Reduced drive and impaired cerebral performance: a new perspective on chronically low blood pressure]

The scientific literature on mental impairment in persons with chronically low blood pressure (using WHO criteria) is systematically reviewed within its physiological context. Subjective symptoms related to hypotension, especially tiredness and listlessness have been adequately demonstrated. There are consistent findings demonstrating deficits in cognitive functions, especially in the fields of concentration and memory. Additionally, contrary to the current views, recent studies provide evidence for an impaired regulation of cerebral blood flow and reduced cerebral perfusion. The resulting deficits in brain function are also reflected in EEG findings. These findings indicate that the marginal attention paid to chronic hypotension in research and clinical practice is no longer justified.