[Clinico-immunological research on patients with different forms of amyotrophic lateral sclerosis]

Changes in the immunological status of patients with lateral amyotrophic sclerosis (LAS) point to the involvement of the autoimmune component into the disease pathogenesis. At the same time there is a correlation between the intensity of immunological disorders and the age, disease pattern and the rate of the pathological process generalization. The lowering of immunological functions is noted to decline with age, possibly leading to the rise of the LAS incidence in older persons.