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Updated: Aug 11, 2026

Preoxygenation Techniques for Tracheal Intubation in Critically Ill Adults Utilizing Oxygen Mask and Noninvasive Ventilation
Published on: December 5, 2025
Factors related to variability in long-term oxygen therapy prevalence
A León Jiménez1, J L López-Campos, F Casas
1Puerta del Mar University Hospital, Cádiz, Spain. antonio.leon@separ.es
Objective:
To analyse the variability of long term oxygen therapy (LTOT) prevalence according to several organisational and population factors.
Methods:
Prospective multicentre survey in 29 public hospitals (population 6,796,964) recording data on the organisational structure of the participating centres and factors related to LTOT prevalence. Official figures were also obtained from local health authorities on the prevalence and cost of LTOT.
Results:
The overall prevalence of LTOT was 184 per 100000 population (range 71-473). There was a specific unit or staff member for LTOT supervision in 17 (58.6%) centres, giving a lower prevalence (169 vs. 237/ 100000; P = 0.03). The altitude of the participating centres (median 92 m, mean 275 m; range 4-848 m) was found to influence LTOT prevalence (r = 0.73; P = 0.005). In the linear regression analysis, the coefficient of determination for altitude was 0.504. Other factors, such as percentage of population aged over 65 years, the attitude of prescribers towards patients with low adherence, current smokers or those with a PaO2 = 61 mmHg, were not related to LTOT prevalence.
Conclusions:
Altitude and the existence of a specific unit or staff member for LTOT supervision significantly influence LTOT prevalence.
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