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Updated: Aug 11, 2026

An Automated Culture System for Use in Preclinical Testing of Host-Directed Therapies for Tuberculosis
Published on: August 16, 2021
Application of the Capilia TB assay for culture confirmation of Mycobacterium tuberculosis complex isolates
D Hillemann1, S Rüsch-Gerdes, E Richter
1National Reference Center for Mycobacteria, Forschungszentrum Borstel, Borstel, Germany. dhillemann@fz-borstel.de
Abstract:
The usefulness of a low-tech rapid test for culture confirmation of Mycobacterium tuberculosis complex, Capilia TB, was tested on 172 mycobacteria-positive clinical samples. The overall sensitivity and specificity were 92.4% and 100%, respectively. In three of nine false-negative isolates a mutation in the mpb64 gene could be detected.
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