Immunology: exhausted T cells perk up

Ets1 represses Blimp1 to promote germinal center T follicular helper cell differentiation during viral infection.

Journal of immunology (Baltimore, Md. : 1950)·2026

Shp-1 regulates the activity of low-affinity T cells specific to endogenous self-antigen during melanoma tumor growth and drives resistance to immune checkpoint inhibition.

Journal for immunotherapy of cancer·2025

Generation of antigen-specific memory CD4 T cells by heterologous immunization enhances the magnitude of the germinal center response upon influenza infection.

PLoS pathogens·2024

Tumour-intrinsic endomembrane trafficking by ARF6 shapes an immunosuppressive microenvironment that drives melanomagenesis and response to checkpoint blockade therapy.

Nature communications·2024

OCA-B/Pou2af1 is sufficient to promote CD4+ T cell memory and prospectively identifies memory precursors.

Proceedings of the National Academy of Sciences of the United States of America·2024

Effector-Phase IL-2 Signals Drive Th1 Effector and Memory Responses Dependently and Independently of TCF-1.

Journal of immunology (Baltimore, Md. : 1950)·2023

An entangling gate for dual-rail erasure qubits.

Nature·2026

An expanded codebook of human transcription factor DNA-binding specificity.

Nature·2026

Upcycling of polyvinyl chloride into polyalphaolefin lubricants.

Nature·2026

The Virtual Tissues foundation model resolves spatial proteomics across scales.

Nature·2026

ZFP36L2 orchestrates stress-adaptive plasticity in regeneration and cancer.

Nature·2026

Unexpected doornail hilar lymph nodes during robot-assisted pulmonary resection: intraoperative challenges and management strategies.

Journal of robotic surgery·2026

Endoscopic Ultrasound-Guided Fine Needle Aspiration Diagnosis of Pancreatic Intraductal Tubulopapillary Neoplasm: A Cytology Case Report.

Diagnostic cytopathology·2026

A miniaturized-tumor culture platform for developing anti-tumor immunotherapies.

Theranostics·2026

Case Report: Exceptional survival with immunotherapy in a patient with EGFR exon 20 insertion (p.S768_D770dup) and high PD-L1 expression.

Frontiers in immunology·2026

Integrated Immunological Analysis of Interactions Between CXCL13+ T Cells and LAMP3+ DC in the Immunotherapy Response of Bladder Cancer.

Molecular carcinogenesis·2026

Super-resolution imaging reveals altered actin architecture at CAR-T cell immune synapses.

The Journal of cell biology·2026

Related Experiment Videos

Immunology: exhausted T cells perk up

Related Concept Videos

Ets1 represses Blimp1 to promote germinal center T follicular helper cell differentiation during viral infection.

Shp-1 regulates the activity of low-affinity T cells specific to endogenous self-antigen during melanoma tumor growth and drives resistance to immune checkpoint inhibition.

Generation of antigen-specific memory CD4 T cells by heterologous immunization enhances the magnitude of the germinal center response upon influenza infection.

Tumour-intrinsic endomembrane trafficking by ARF6 shapes an immunosuppressive microenvironment that drives melanomagenesis and response to checkpoint blockade therapy.

OCA-B/Pou2af1 is sufficient to promote CD4+ T cell memory and prospectively identifies memory precursors.

Effector-Phase IL-2 Signals Drive Th1 Effector and Memory Responses Dependently and Independently of TCF-1.

An entangling gate for dual-rail erasure qubits.

An expanded codebook of human transcription factor DNA-binding specificity.

Upcycling of polyvinyl chloride into polyalphaolefin lubricants.

The Virtual Tissues foundation model resolves spatial proteomics across scales.

ZFP36L2 orchestrates stress-adaptive plasticity in regeneration and cancer.

Unexpected doornail hilar lymph nodes during robot-assisted pulmonary resection: intraoperative challenges and management strategies.

Endoscopic Ultrasound-Guided Fine Needle Aspiration Diagnosis of Pancreatic Intraductal Tubulopapillary Neoplasm: A Cytology Case Report.

A miniaturized-tumor culture platform for developing anti-tumor immunotherapies.

Case Report: Exceptional survival with immunotherapy in a patient with EGFR exon 20 insertion (p.S768_D770dup) and high PD-L1 expression.

Integrated Immunological Analysis of Interactions Between CXCL13+ T Cells and LAMP3+ DC in the Immunotherapy Response of Bladder Cancer.

Super-resolution imaging reveals altered actin architecture at CAR-T cell immune synapses.

Related Experiment Videos

Immunology: exhausted T cells perk up

Related Concept Videos

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