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[Studies on the chemical constituents in root of Coleus forskohlii]
Ling-ling Xu1, Jie Lu, Wei-jia Li
1Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210038, China.
Objective:
To study the chemical constituents in root of Coleusforskohlii.
Method:
The chemical constituents were isolated by column chromatography. The structures were elucidated on the basis of IR, MS, 1H-NMR, 13C-NMR and 2D-NMR experiments.
Result:
Six compounds were obtained and the structures were identified as 14-deoxycoleon U (1), demethylcryptojaponol (2), alpha-amyrin (3), betulic acid (4), alpha-cedrol (5) and beta-sitosterol (6).
Conclusion:
Compounds 1 and 2 were isolated from the genus Coleus for the first time. Compounds 3 and 4 were isolated from C. forskohlii for the first time.
