[Evaluation of clinical effects of amine fluoride/stannous fluoride containing toothpaste and mouthrinse]

The aim of the study was to evaluate the effects of amine fluoride (AmF)/stannous fluoride (SnF2) containing toothpaste and mouthrinse on gingival health of young adults. Altogether 42 persons participated in the study (mean age: 28.3 +/- 7.2) and were evaluated for Plaque Index (PI) (Silness and Löe, 1963) and Gingival Index (GI) (Löe and Silness, 1964). The probands were randomly divided into two groups, both of them used AmF/SnF2 containing toothpaste twice a day for three minutes toothbrushing. One group (combined group) after toothbrushing rinsed with mouthrinse containing AmF/AnF2 combination. After four weeks the participants were re-examined. At the end of the study statistically significant decrease was found in dental plaque (PI) and gingival index (GI) values. Values of PI and GI in the group using only toothpaste were as follows (mean +/- S.D.): PI values-baseline: 1.03 +/- 0.20; final: 0.60 +/- 0.13; p<0.001; GI values-baseline: 0.87 +/- 0.22; final: 0.505 +/- 0.22; p<0.01. The values of PI and GI in the combined group were as follows: PI values-baseline: 1.10 +/- 0.20; final: 0.52 +/- 0.10; p<0.001; GI values- baseline: 1.05 +/- 0.27; final: 0.50 +/- 0.17; p< +/- 0.001. The reduction of PI and GI values was significant in all groups but it was higher in the combined (toothpaste + mouthrinse) group than in the one using toothpaste only. It is concluded that regular use of AmF/AnF2 toothpaste has a beneficial effect for reduction of plaque accumulation but its effect can be enhanced with additional use of Am/SnF2 containing mouthrinse.