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Published on: July 21, 2022
Ringing the alarm bells: signalling and apoptosis in influenza virus infected cells
Stephan Ludwig1, Stephan Pleschka, Oliver Planz
1Institute of Molecular Virology (IMV) Westfaelische-Wilhelms-University, Von-Esmarch Str. 56, D-48161 Muenster, Germany. ludwigs@uni-muenster.de
Abstract:
Small RNA viruses such as influenza viruses extensively manipulate host-cell functions to support their replication. At the same time the infected cell induces an array of defence mechanisms to fight the invader. These processes are mediated by a variety of intracellular signalling cascades. Here we will review the current knowledge of functional kinase signalling and apoptotic events in influenza virus infected cells and how these viruses have learned to misuse these cellular responses for efficient replication.
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