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Related Experiment Videos

Prevalence, characteristics and implications of premature ejaculation/rapid ejaculation.

Stanley E Althof1

  • 1Department of Urology, Case School of Medicine and Center for Marital and Sexual Health of South Florida, West Palm Beach, Florida 33401, USA. sxa6@po.cwru.edu

The Journal of Urology
|February 14, 2006
PubMed
Summary

Premature ejaculation (PE) affects 20-30% of men, yet lacks approved treatments and clear diagnostic criteria. Further research is needed for effective therapies and improved patient-physician communication regarding this common male sexual dysfunction.

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Area of Science:

  • Male sexual dysfunction
  • Urology
  • Sexual medicine

Background:

  • Premature ejaculation/rapid ejaculation (PE/RE) is a prevalent male sexual dysfunction with significant impact.
  • Understanding of PE/RE pathophysiology, etiology, and impact remains incomplete.
  • There is a lack of approved medications specifically indicated for PE/RE treatment.

Purpose of the Study:

  • To increase awareness of PE/RE prevalence, characteristics, and impact.
  • To encourage physician-patient dialogue concerning PE/RE.
  • To stimulate the development of novel therapeutic strategies for PE/RE.

Main Methods:

  • A comprehensive literature search was conducted using MEDLINE and other relevant sources.
  • Articles reviewed included those on PE/RE pathophysiology, etiology, impact, diagnosis, and treatment.

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  • Sexual medicine journals, texts, and congress abstracts were also analyzed.

    • Main Results:

    • No universally accepted definition, diagnostic criteria, or validated screening tools for PE/RE exist.
    • Current treatments, including off-label antidepressants, topical anesthetics, and PDE5 inhibitors, have limitations.
    • Psychological counseling and behavioral therapies are valuable but have limited resources.

    Conclusions:

    • The high prevalence (20-30%) and negative quality of life impact necessitate improved diagnostic and treatment standards for PE/RE.
    • There is a critical need for specifically indicated, on-demand medications for PE/RE.
    • Integrated approaches combining pharmacotherapy with behavioral therapies focusing on pleasure, arousal, control, confidence, and satisfaction show promise.