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Updated: Aug 11, 2026
Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus (KSHV)
Published on: September 14, 2010
[A case-control study on risk factor of Kaposi's sarcoma in Xinjiang]
Jiang-mei Qin1, Feng Li, Xiao-hua Tan
1Laboratory of Xinjinag Endemic and Ethnic Disease, Shihezi University, Shihezi 832002, China.
Objective:
To analyse related risk factors of classic Kaposi' s sarcoma in Xinjiang.
Methods:
A 1:4 case-control study was used and the conditional logistic regression model was performed in this study. Cases were followed up in Xinjiang while controls were selected by the same sex, nation and age within 5 years with cases.
Results:
Interleukin-6,vascular endothelial growth factor, beta-MG, neopterin, human herpevirus 8, were found to be associated with Kaposi's sarcoma risk in one-way variance model while beta2 -MG and human herpevirus 8 entered the multiple conditional logistic regression model, and their ORs were 1.002(95%CI: 1.000-1.003), 81.041 (95%CI: 1.790-3669.620).
Conclusion:
There was a correlate relationship between beta2 -MG and classic Kaposi's sarcoma being found that human herpevirus 8 exposure related factors seemed to have played important roles on classic Kaposi's sarcoma in Xinjiang.
