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Updated: Aug 11, 2026

Development of an In Vitro Ocular Platform to Test Contact Lenses
Published on: April 6, 2016
Initial clinical testing of a holographic non-invasive contact lens glucose sensor
Angelika Domschke1, Wayne F March, Satyamoorthy Kabilan
1CIBA Vision Corporation, Duluth, Georgia, USA.
Introduction:
The purpose of the present study was to determine the effectiveness of a new holographic contact lens glucose sensor for the non-invasive monitoring of blood glucose.
Methods:
One fasting normal subject was given an oral challenge consisting of 44 g of glucose. The contact lens hologram signal and fingerstick blood glucose were measured over a 26- min period.
Results:
The contact lens hologram signal appeared to track blood glucose well. The contact lens was comfortable and well tolerated.
Conclusion:
The holographic contact lens glucose sensor shows promise as a non-invasive home glucose monitor.

