Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cardiovascular autonomic function tests in cluster headache.

J A van Vliet1, A A Vein, M D Ferrari

  • 1Department of Neurology and Clinical Neurophysiology, Leiden University Medical Centre, Leiden, the Netherlands.

Cephalalgia : an International Journal of Headache
|February 14, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Placebo Response in Acute and Prophylactic Treatment of Migraine: A Systematic Review and Meta-Analysis Covering 36 Years of Research.

Neurologic clinics·2025
Same author

A literature review and evidence-based evaluation of the Dutch national immunisation schedule yield possibilities for improvements.

Vaccine: X·2024
Same author

Diagnostic and societal impact of implementing the syncope guidelines of the European Society of Cardiology (SYNERGY study).

BMC medicine·2023
Same author

Automated spike and seizure detection: Are we ready for implementation?

Seizure·2023
Same author

Automated seizure detection in an EMU setting: Are software packages ready for implementation?

Seizure·2022
Same author

Automated spike detection: Which software package?

Seizure·2022
Same journal

Cerebrovascular risk with calcitonin gene-related peptide monoclonal antibodies versus onabotulinumtoxinA in patients with migraine: A real-world pharmacoepidemiologic study in the National Institutes of Health All of Us Research Program.

Cephalalgia : an international journal of headache·2026
Same journal

Burning mouth syndrome and oral dysaesthetic/perceptual symptoms: Toward clinically actionable boundaries.

Cephalalgia : an international journal of headache·2026
Same journal

Effectiveness and clinical predictors of rimegepant for acute vertigo in vestibular migraine: A real-world cohort study.

Cephalalgia : an international journal of headache·2026
Same journal

Efficacy of digital therapeutic sinCephalea for personalised nutrition versus control for migraine prevention: A 12-week open-label randomised clinical trial.

Cephalalgia : an international journal of headache·2026
Same journal

SafeTy and effectiveness of Atogepant accoRding to the IHS outcome categories: A multicentric, prospective observational study in real life (the 24-week STAR study).

Cephalalgia : an international journal of headache·2026
Same journal

Placebo or active comparator in chronic migraine trials: Balancing evidence and practicality.

Cephalalgia : an international journal of headache·2026
See all related articles

Cluster headache (CH) patients show no significant cardiovascular autonomic function changes during a cluster period, outside of active attacks. This suggests systemic cardiovascular control remains stable between CH attacks.

Area of Science:

  • Neurology
  • Autonomic Neuroscience

Background:

  • Facial autonomic symptoms are common in cluster headache (CH) attacks.
  • Cardiovascular autonomic function in CH patients requires further investigation, particularly during different disease stages.

Purpose of the Study:

  • To evaluate changes in general autonomic function in CH patients during a cluster period, specifically outside of active attacks.
  • To determine if cardiovascular autonomic function differs between periods with and without active cluster headaches.

Main Methods:

  • Conducted autonomic function tests (AFT) on 18 CH patients during and outside of a cluster period, but not during an attack.
  • Assessed heart rate variability (HRV) through deep breathing, standing, and Valsalva maneuver.
  • Measured blood pressure (BP) changes during rest, standing, and sustained handgrip.

Related Experiment Videos

Main Results:

  • No significant differences were found in most AFT measurements between the cluster and non-cluster periods.
  • A statistically significant increase in diastolic blood pressure (BP) at rest was observed during the cluster period (P = 0.04).

Conclusions:

  • Systemic cardiovascular autonomic control does not appear to be significantly impaired in CH patients during a cluster period when not experiencing an active attack.
  • The observed increase in resting diastolic BP warrants further investigation in the context of cluster headache pathophysiology.