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Updated: Aug 11, 2026

Isolation of Human Islets from Partially Pancreatectomized Patients
Published on: July 30, 2011
[Extrapancreatic tumour-induced hypoglycaemia]
Rasmus Rabøl1, Jens Frystyk Nielsen, Preben Kirkegaard
1Storstrøms Sygehus, Medicinsk afdeling, Arhus Universitetshospital, Medicinsk Forskningslaboratorium, Klinisk Institut og H:S Rigshospitalet, Patologiafdeling PA, og Kirurgisk Gastroenterologisk Klinik CTX .
Abstract:
A 53-year-old non-diabetic man was admitted with hypoglycaemia, neuroglycopenic symptoms and acromegaloid facial swelling. Serum insulin concentration was suppressed, but the free concentration of insulin-like growth factor (IGF-II) was markedly elevated. CT scan demonstrated a large tumour in the liver. The histology showed a benign, solid, fibrous tumour. A hemihepatectomy was performed, and a 3.6 kg tumour was removed. Postoperatively, the blood glucose concentration and the concentration of free IGF-II returned to normal and the acromegaloid facial features disappeared.
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