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Updated: Aug 11, 2026

Modification and Functionalization of the Guanidine Group by Tailor-made Precursors
Published on: April 27, 2017
Application of neutral amidines and guanidines in coordination chemistry
1Department of Chemistry, University of Sussex, Falmer, Brighton, UKBN1 9QJ. m.p.coles@sussex.ac.uk
Abstract:
The aim of this perspective is to highlight the continued development and application of amidines and guanidines as neutral, N-based donor ligands in coordination chemistry. From a sporadic interest dating back to the 1980s, work on these two closely related classes of compounds has steadily grown, with examples of evermore sophisticated substitution about the common ligand framework being developed to address specific problems in a number of fields of chemistry. These compounds have shown varied coordination modes at metals from across the periodic table, and examples of their application in a number of catalytic processes are emerging as the field matures.
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