Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Organ dysfunction during sepsis.

Suveer Singh1, Timothy W Evans

  • 1Chelsea and Westminster Hospital, Department of Intensive Care Medicine, 369 Fulham Road, SW10 9NH, London, UK. suveer.singh@imperial.ac.uk

Intensive Care Medicine
|February 14, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Virtual Reality versus Augmented Reality Bronchoscopy Simulation-Based Training: A Randomised Controlled Trial to Compare Navigation Performance and Cognitive Load in Novice Bronchoscopists.

Respiration; international review of thoracic diseases·2026
Same author

Infection point of care tests bridge the experience gap of antibiotic STOP decisions: clinicians versus students.

The Journal of antimicrobial chemotherapy·2026
Same author

Deep learning framework for bronchoscopic diagnosis of burn inhalation injury.

Burns : journal of the International Society for Burn Injuries·2025
Same author

Evaluating the association between bronchoscopic severity of burns-related smoke inhalation injury and clinical outcomes: A systematic review and meta-analysis.

Burns : journal of the International Society for Burn Injuries·2025
Same author

Artificial intelligence in bronchoscopy: a systematic review.

European respiratory review : an official journal of the European Respiratory Society·2025
Same author

Evaluating inter-and intra-rater reliability in the bronchoscopic grading of burn inhalation injury: The iBRONCH-BII study.

Burns : journal of the International Society for Burn Injuries·2025
Same journal

Publisher Correction: Current knowledge and challenges of sepsis-associated encephalopathy.

Intensive care medicine·2026
Same journal

Prehospital airway and ventilatory management: a collaborative and narrative review.

Intensive care medicine·2026
Same journal

Rapid coma with bilateral basal ganglia involvement.

Intensive care medicine·2026
Same journal

From size to function: moving beyond body mass index to frailty and central adiposity phenotypes.

Intensive care medicine·2026
Same journal

Effects of a clinical metagenomics intervention on clinical outcomes, healthcare costs, and health-related quality of life in patients with sepsis or septic shock: results of the randomized-controlled DigiSep trial.

Intensive care medicine·2026
Same journal

Hypercalcemia in intensive care unit: pathophysiological mechanisms and clinical implications.

Intensive care medicine·2026
See all related articles

Multiple organ dysfunction syndrome (MODS) is a leading cause of sepsis mortality. Advances in understanding pathophysiology, monitoring, and management strategies offer hope for reducing deaths from sepsis-associated MODS.

Area of Science:

  • Critical Care Medicine
  • Pathophysiology
  • Sepsis Research

Background:

  • Multiple organ dysfunction syndrome (MODS) is the primary driver of mortality in sepsis.
  • Understanding the pathophysiology of MODS is crucial for effective sepsis management.

Purpose of the Study:

  • To review the historical understanding and advancements in managing sepsis-induced multiple organ dysfunction syndrome.
  • To highlight emerging methodologies and therapeutic interventions for sepsis.

Main Methods:

  • Literature review of historical developments in sepsis and MODS research.
  • Discussion of novel monitoring and severity scoring systems.
  • Analysis of systematic management strategies and therapeutic interventions.

Related Experiment Videos

Main Results:

  • Significant progress has been made in understanding sepsis pathophysiology over the past 40 years.
  • New tools for monitoring and scoring illness severity in sepsis have been developed.
  • Systematic approaches to managing organ dysfunction in sepsis are evolving.

Conclusions:

  • Improved understanding and novel methodologies are key to reducing sepsis-associated mortality.
  • The development of effective therapeutic interventions holds promise for better patient outcomes.
  • Continued research and application of these advancements are essential for combating sepsis.