Related Experiment Video
Updated: Aug 18, 2026

09:43
Primary Orthotopic Glioma Xenografts Recapitulate Infiltrative Growth and Isocitrate Dehydrogenase I Mutation
Published on: January 14, 2014
Morphological observations of dysplastic gliomas heterotransplanted to experimental animals
Acta Neuropathologica
|January 1, 1975
Abstract:
Observations concerning transplantation of 5 cases of malignant dysplastic gliomas to the anterior chamber of the guinea-pig eye have been presented. This type of gliomas, composed mainly of cytoplasm-abundant cells, show weak transplantability, slow rate of growth, and particular tendency to degeneration and necrosis. At the same time, in subsequent passages, an intensive proliferation of small-cell component occurs, comparing with cytoplasm-abundant cells.

