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[Acute multifocal osteomyelitis caused by haemolytic group B streptococci]
Hanne Pedersen1, Jørgen H Engberg, Peter S Oturai
1Amtssygehuset i Roskilde, Geriatrisk Afdeling, Statens Serum Institut. hannepedersen@dadlnet.dk
Abstract:
Invasive infections due to group B streptococci (Streptococcus agalactiae) usually occur in the peri- and neonatal setting or in adults with chronic underlying diseases. In the presented case a severe infection of haematogenous osteomyelitis caused by group B streptococci in a previously healthy 68-year-old woman is reported. Group B streptococci were isolated in three of three blood culture bottles drawn from the patient at the time of admission to hospital due to fever of unknown cause and pain in the upper and lower extremities as well as the back. A technetium scan showed involvement of the left shoulder, the left sacroilial joint, Th-9, Th-12 and L5. In addition, there was increased activity in the left foot, the right side of the mandibula and probably both hands (insufficiently scanned). The patient was successfully treated with penicillin G and subsequently with oral penicillin V for a total of 12 weeks.
Insights
This case report details a severe group B Streptococcus (Streptococcus agalactiae) osteomyelitis infection in a healthy older woman. The patient recovered fully after a 12-week course of penicillin treatment.
Area of Science:
- Infectious Diseases
- Bacteriology
- Clinical Case Study
Background:
- Group B Streptococcus (Streptococcus agalactiae) typically causes invasive infections in neonates or adults with chronic conditions.
- Hematogenous osteomyelitis is a serious bone infection that can arise from bloodstream spread of bacteria.
Observation:
- A previously healthy 68-year-old woman presented with fever of unknown origin and widespread pain.
- Blood cultures confirmed invasive infection with Group B Streptococcus.
- Technetium scan revealed multifocal osteomyelitis affecting the shoulder, sacroiliac joint, spine (Th-9, Th-12, L5), foot, jaw, and hands.
Findings:
- The patient was diagnosed with severe, multifocal, hematogenous osteomyelitis caused by Group B Streptococcus.
- The infection presented atypically in a healthy elderly individual without typical risk factors.
Implications:
- This case highlights the potential for Group B Streptococcus to cause severe invasive disease, including osteomyelitis, in previously healthy older adults.
- Prompt diagnosis and appropriate antibiotic therapy, such as penicillin G and V, are crucial for successful treatment outcomes.
- Further research may be warranted to understand the epidemiology of Group B Streptococcus infections in non-pregnant, non-elderly populations.
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