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Updated: Aug 11, 2026

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation
Published on: March 24, 2023
[Contact dermatitis from Agave americana]
Pablo de la Cueva1, Mateo González-Carrascosa, Minia Campos
1Servicio de Dermatología, Hospital General Universitario Gregorio Marañón, Madrid, Spain. pdelacueva@yahoo.com
Abstract:
Numerous plant species and their derivatives can cause skin reactions through a variety of mechanisms: irritative contact dermatitis, allergic contact dermatitis, contact urticaria and photodermatitis. We present a case of irritative contact dermatitis after exposure to the sap of Agave americana. The skin symptoms in this case have only been described on rare occasions; although this condition usually presents with a papulovesicular rash, in this patient it appeared as purpuric lesions in the contact area.
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