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Published on: August 1, 2018
[Clinico-hemodynamic typification of alcoholics with various central circulatory disorders]
Insights
This study details the autonomic-somatic and cardiovascular aspects of alcohol withdrawal and delirium. It proposes a new treatment approach for alcoholism based on individual hemodynamic profiles.
Area of Science:
- Cardiology
- Neurology
- Addiction Medicine
Background:
- Alcoholism significantly impacts autonomic and somatic functions, leading to withdrawal and delirium.
- Cardiovascular and hemodynamic deviations are critical components of these conditions.
Purpose of the Study:
- To analyze the clinical presentation of autonomic-somatic and cardiovascular components in alcoholic abstinence and delirium.
- To investigate the role of hemodynamic disorders in alcoholism.
- To develop a new approach for differentiated treatment of alcoholic patients.
Main Methods:
- Tetrapolar chest rheography was used to examine 137 patients with stage II and III alcoholism.
- Patients were categorized into abstinent (64) and delirious (73) syndromes.
- Clinical and hemodynamic parameters, including phases of hemodynamic decompensation, were analyzed over time.
Main Results:
- Main types of hemodynamic disorders were identified in alcoholic patients.
- The study demonstrated the role of alcoholic cardiomyopathy in cardiovascular and somatovegetative manifestations.
- Three clinico-hemodynamic types corresponding to hemodynamic disorders were established.
Conclusions:
- A novel, individualized treatment strategy for alcoholism was developed based on clinico-hemodynamic types.
- Optimally computed drug doses targeting hemodynamics are recommended for differentiated patient care.
Abstract:
A study was made of the clinical picture of autonomic-somatic++ components of alcoholic abstinence and delirium as well as of the role of cardiovascular (hemodynamic) deviations. Using tetrapolar chest rheography the main types of hemodynamic disorders were described on a material of a random examination of 137 patients with stage II and III alcoholism. Of these, 64 patients were with the abstinent syndrome and 73 with the delirious syndrome according to the growth of the status gravity. Analysis of the clinical picture of the disease was first performed over time on the basis of the clinico-hemodinamic + parameters and phases of hemodynamic decompensation. The role of alcoholic cardiomyopathy in the general structure of the cardiovascular and somatovegetative manifestations was shown as dependent on variants of abstinence and delirium. Based on three clinico-hemodynamic++ types equivalent to the types of hemodynamic disorders, a new approach was applied to the differentiated treatment of alcoholic patients depending on their individual features, using optimally computed drug doses influencing the hemodynamics.
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