Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Evaluating and managing hypogammaglobulinemia.

Mark E Rose1, David M Lang

  • 1Section of Adult Allergy and Immunology, Department of Pulmonary, Allergy, and Critical Care Medicine, The Cleveland Clinic Foundation, OH 44195, USA.

Cleveland Clinic Journal of Medicine
|February 16, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The 2025 WAO Guidelines for the classification, diagnosis, and treatment of hereditary angioedema, with consideration of worldwide disparities.

The World Allergy Organization journal·2026
Same author

Iodinated Contrast Media and Anaphylaxis.

Immunology and allergy clinics of North America·2026
Same author

Chronic Urticaria: The Long and Winding Road.

The journal of allergy and clinical immunology. In practice·2026
Same author

An opportunity to improve the quality of care for patients with chronic spontaneous urticaria: A reimagined 3-step real-world study protocol.

The journal of allergy and clinical immunology. Global·2026
Same author

Non-injectable versus injectable epinephrine treatment thresholds for acute allergic reactions in the community.

The journal of allergy and clinical immunology. In practice·2026
Same author

Global disparities in adrenaline access: A World Allergy Organization call for equity in anaphylaxis care.

The World Allergy Organization journal·2025

Low immunoglobulin levels can cause frequent infections. This article covers primary and secondary hypogammaglobulinemia, including evaluation and management strategies for patients.

Area of Science:

  • Immunology
  • Infectious Diseases

Background:

  • Frequent or recurrent bronchopulmonary and sinus infections can indicate underlying immune system dysfunction.
  • Low levels of immunoglobulins, a condition known as hypogammaglobulinemia, are a common cause of such recurrent infections.

Purpose of the Study:

  • To describe the common primary (idiopathic) and secondary forms of hypogammaglobulinemia.
  • To outline the diagnostic evaluation process for patients presenting with suspected hypogammaglobulinemia.
  • To detail the management strategies for hypogammaglobulinemia.

Main Methods:

  • Review of primary and secondary hypogammaglobulinemia.
  • Description of diagnostic approaches including laboratory testing and clinical assessment.
  • Outline of therapeutic interventions.

Related Experiment Videos

Main Results:

  • Hypogammaglobulinemia presents as a significant risk factor for recurrent infections.
  • Primary hypogammaglobulinemia is often idiopathic, while secondary forms arise from other conditions.
  • Effective management involves accurate diagnosis and tailored treatment plans.

Conclusions:

  • Recognizing hypogammaglobulinemia is crucial for managing patients with recurrent infections.
  • A systematic approach to evaluation and management can improve patient outcomes.
  • Understanding the different forms of hypogammaglobulinemia aids in targeted therapy.