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[Surveillance study on bacteriological etiology of 8371 children with diarrhea]
Abstract:
The results of stool cultures from 8371 children of 0-13 years old with diarrhea during the years of January 1981 to December 1989 in Shanghai area are reported. 2906 strains of enteropathogenic bacteria were isolated, with total detection rate of 34.72%. Shigella were still the most common pathogens in 1981-1984, and Campylobacter jejuni took second place, whereas from 1985 on Campylobacter exceeded Shigella as the first pathogenic bacteria of children's diarrhea. Except in 1987 and 1988 Shigella sounei predominated over Shigella flexneri in detection rate within the past nine years, the detection rates of EPEC and Salmonella were lower. It was significant that Salmonella typhimurium was about half the number for Salmonella non typhi. During 1986 and 1987 we specially isolated and identified Vibrionaceae bacteria with 130 strains of Vibironaceae detected, occupying third place among pathogens of children's diarrhea in these two years, and among which aeromonas were the most common. This article analyses in detail the distribution of enteropathogenic bacteria with respect to their species, genus and serum type.
Insights
Campylobacter jejuni became the leading cause of childhood diarrhea in Shanghai by 1985, surpassing Shigella. This study tracked enteropathogenic bacteria in children over nine years.
Area of Science:
- Pediatric Infectious Diseases
- Microbiology
- Public Health
Background:
- Diarrheal diseases remain a significant health concern for children globally.
- Understanding the etiological agents of pediatric diarrhea is crucial for effective treatment and prevention strategies.
Purpose of the Study:
- To analyze the trends and distribution of enteropathogenic bacteria causing diarrhea in children aged 0-13 in Shanghai from 1981 to 1989.
- To identify shifts in the predominant bacterial pathogens over the study period.
Main Methods:
- Stool cultures were performed on 8371 children presenting with diarrhea.
- Isolated bacterial strains were identified to species, genus, and serum type.
- Data were analyzed to determine detection rates and trends over nine years.
Main Results:
- A total of 2906 enteropathogenic bacterial strains were isolated, with an overall detection rate of 34.72%.
- Campylobacter jejuni emerged as the most common pathogen by 1985, overtaking Shigella.
- Shigella sounei was more prevalent than Shigella flexneri in most years, and Salmonella typhimurium constituted about half of all Salmonella isolates.
Conclusions:
- The epidemiological landscape of pediatric diarrhea in Shanghai shifted, with Campylobacter jejuni becoming the dominant pathogen.
- Vibrionaceae, particularly Aeromonas, also represented a significant proportion of pediatric diarrhea cases during specific years.
- Detailed analysis of bacterial species, genus, and serotype provides valuable insights for public health interventions.