Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Bone morphogenic protein science and studies.

Joseph M Lane1

  • 1Hospital for Special Surgery, New York, NY 10021, USA. lanej@hss.edu

Journal of Orthopaedic Trauma
|February 16, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical impact of acute symptomatic vertebral fractures in the United States: A patient survey and chart review.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2026
Same author

Multidisciplinary Approach to a Transverse Periprosthetic Femur Fracture in a Short-Statured Patient: A Case Report.

JBJS case connector·2025
Same author

High incidence of multi-joint osteonecrosis in first year following treatment for acute lymphoblastic leukemia.

Leukemia & lymphoma·2025
Same author

Skeletal Stem Cells: A Basis for Orthopaedic Pathology and Tissue Repair.

The Journal of bone and joint surgery. American volume·2024
Same author

Racial and Ethnic Disparities in Hip Fracture Surgery: A Systematic Review and Meta-Analysis.

HSS journal : the musculoskeletal journal of Hospital for Special Surgery·2024
Same author

What's New in Osteoporosis: Emphasis on the Aging Athlete.

The Journal of bone and joint surgery. American volume·2024
Same journal

Intrapelvic Plate Fixation of Associated Both Column Acetabular Fracture in an Elderly Patient.

Journal of orthopaedic trauma·2026
Same journal

Utilization of a Utility Plate in the Treatment of Periprosthetic Humeral Shaft Fractures Around a Shoulder Arthroplasty.

Journal of orthopaedic trauma·2026
Same journal

Surgical Treatment of an Acetabular Fracture Using a Novel Intrapelvic Acetabular System.

Journal of orthopaedic trauma·2026
Same journal

Reliability of modified Radiographic Union Scale for Tibial Fractures (mRUST) Scores in Ballistic Lower Extremity Trauma.

Journal of orthopaedic trauma·2026
Same journal

Early Definitive Fixation and Risk of Deep Surgical-Site Infection After Tibial Plateau ORIF: A Systematic Review and Meta-analysis.

Journal of orthopaedic trauma·2026
Same journal

Fragmented Sleep And Opioid Medication Utilization During Hospitalization Following Orthopaedic Trauma.

Journal of orthopaedic trauma·2026
See all related articles

Bone morphogenic proteins (BMPs) show promise in orthopaedic surgery for spine fusion and fracture healing. This article details recombinant BMP development and preclinical trial use.

Area of Science:

  • Orthopaedic Surgery
  • Biotechnology
  • Regenerative Medicine

Background:

  • Growth factors, specifically bone morphogenic proteins (BMPs), are osteoinductive.
  • BMPs have demonstrated success in clinical applications like spine fusion and fracture repair.

Purpose of the Study:

  • To describe the development and production processes of recombinant BMPs.
  • To summarize the findings from preclinical trials involving recombinant BMPs.

Main Methods:

  • Review of BMP development and production methodologies.
  • Analysis of data from preclinical studies on BMP efficacy and safety.

Main Results:

  • Successful development and production of recombinant BMPs.

Related Experiment Videos

  • Positive outcomes in preclinical trials for spine fusion and fracture healing.

    • Conclusions:

    • Recombinant BMPs represent a promising therapeutic option in orthopaedics.
    • Further clinical investigation is warranted based on preclinical data.