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Systematic Assessment of Well-Being in Mice for Procedures Using General Anesthesia
Published on: March 20, 2018
Utilities of the post-anesthesia state derived by the standard gamble method in surgical patients
Saifudin Rashiq1, Diane Edlund, Bruce D Dick
1Department of Anesthesiology & Pain Medicine, University of Alberta, Edmonton, AB T6G 2G3, Canada. srashiq@ualberta.ca
Background:
There are no published utilities for the post-anesthesia state obtained by the standard gamble method (SG).
Methods:
We obtained utilities for postoperative pain, nausea, vomiting, urinary retention and myalgia from 100 adults prior to elective surgery using SG.
Results:
20% of volunteer participants could not demonstrate a satisfactory understanding of the SG process. Median utilities for each adverse effect were all very close to 1.0, and no statistically significant differences were found between them.
Conclusion:
Our results suggest that the avoidance of anesthesia related side effects and pain is not viewed by patients prior to surgery as being worthy of the taking of even a miniscule risk of death. This may affect the decision to utilize anesthesia techniques that trade a lower incidence of common side effects for a very low but finite risk of a catastrophic complication.
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