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Chronic zosteriform cutaneous leishmaniasis.
1Department of Dermatology, Imam Hospital, Ahwaz Jundishapour University of Medical Sciences, Ahwaz, Iran. momidian@yahoo.com
Indian Journal of Dermatology, Venereology and Leprology
|February 17, 2006
Summary
This study reports the first case of multidermatomal zosteriform cutaneous leishmaniasis (CL). The rare CL variant was resistant to standard treatment but responded to a combination therapy.
Area of Science:
- Dermatology
- Infectious Diseases
- Parasitology
Background:
- Cutaneous leishmaniasis (CL) presents with diverse clinical manifestations.
- Unusual CL variants, including zosteriform patterns, are infrequently documented.
- Morphological variations may stem from host immune response or parasite strain differences.
Observation:
- A patient in Iran presented with CL in a rare multidermatomal zosteriform pattern on the back and buttock.
- This represents the first documented instance of multidermatomal zosteriform CL.
- The lesions exhibited resistance to conventional CL treatments.
Findings:
- The patient's multidermatomal zosteriform CL responded effectively to a combination regimen.
- Treatment included meglumine antimoniate, allopurinol, and cryotherapy.
- This combination therapy proved successful for a treatment-resistant CL case.
Implications:
- This case expands the known clinical spectrum of cutaneous leishmaniasis.
- It highlights a potential therapeutic strategy for rare and resistant CL presentations.
- Further research into host-parasite interactions in unusual CL variants is warranted.