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A Method for Selecting Structure-switching Aptamers Applied to a Colorimetric Gold Nanoparticle Assay
12:31

A Method for Selecting Structure-switching Aptamers Applied to a Colorimetric Gold Nanoparticle Assay

Published on: February 28, 2015

Colorimetric screening of DNA-binding molecules with gold nanoparticle probes

Min Su Han1, Abigail K R Lytton-Jean, Byung-Keun Oh

  • 1Department of Chemistry, Evanston, IL, 60208-3113, USA.

Angewandte Chemie (International Ed. in English)
|February 17, 2006
PubMed
Abstract

No abstract available in PubMed .

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Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...