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Measuring Bacterial Load and Immune Responses in Mice Infected with Listeria monocytogenes
12:50

Measuring Bacterial Load and Immune Responses in Mice Infected with Listeria monocytogenes

Published on: August 9, 2011

[Listeria monocytogenes meningitis complicated after operation for thoracic aortic aneurysm]

Yuichiro Yokoyama1, T Suzuki, Y Yamashita

  • 1Department of First Surgery, Faculty of Medicine, Kagawa University, Kagawa, Japan.

Kyobu Geka. the Japanese Journal of Thoracic Surgery
|February 18, 2006
PubMed

Insights

A 71-year-old male with a thoracic aortic aneurysm developed Listeria monocytogenes infection post-surgery, leading to meningitis and pericarditis. This case highlights the high mortality rate of listeriosis, emphasizing the need for prompt recognition and treatment.

Area of Science:

  • Cardiovascular Surgery
  • Infectious Diseases
  • Pathology

Background:

  • A 71-year-old male presented with impending rupture of a thoracic aortic aneurysm.
  • The saccular aneurysm was located in the lesser curvature of the aortic arch.

Observation:

  • Emergency surgical repair using an artificial graft under deep hypothermic circulatory arrest was performed.
  • Postoperatively, the patient experienced a sudden decline in consciousness and fever one week after the procedure.

Findings:

  • Autopsy revealed meningitis and pericarditis caused by Listeria monocytogenes.
  • Listeriosis, a zoonotic disease, has a high mortality rate when it occurs.

Implications:

  • This case underscores the critical importance of considering and rapidly diagnosing Listeria monocytogenes infection in post-operative patients presenting with neurological and febrile symptoms.
  • Prompt recognition and appropriate antimicrobial therapy are crucial for improving outcomes in listeriosis, particularly in immunocompromised or post-surgical individuals.

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