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Updated: Aug 7, 2026

An In Vitro Model of a Parallel-Plate Perfusion System to Study Bacterial Adherence to Graft Tissues
Published on: January 7, 2019
[Mitral valvuloplasty utilizing a posterior leaflet patch for healed infective endocarditis; report of a case]
Shingo Taguchi1, S Ishii, H Okuyama
1Department of Cardiovascular Surgery, The Jikei University School of Medicine, Tokyo, Japan.
Abstract:
A 63-year-old man was diagnosed as having grade IV mitral regurgitation (MR). Intraoperative examination revealed perforation (13x7 mm) of the anterior mitral leaflet (AML) and prolapse of the posterior mitral leaflet (PML). The prolapsing part of the PML was resected as a rectangle and the AML perforation was covered with this resected PML patch. A Carpentier-Edwards rigid ring (30 mm) was used to secure the mitral valve annulus after suturing the PML. The patient had an uneventful course after surgery and postoperative echocardiography showed no regurgitation.
Insights
This study presents a novel surgical technique for severe mitral regurgitation, successfully repairing an anterior mitral leaflet perforation using a posterior leaflet patch. Post-operative results showed no mitral regurgitation, indicating a promising treatment approach.
Area of Science:
- Cardiovascular Surgery
- Cardiac Valve Repair
- Mitral Valve Disease
Background:
- Severe mitral regurgitation (MR) poses significant risks.
- Surgical repair of complex mitral valve defects requires innovative techniques.
- Anterior mitral leaflet perforation and posterior mitral leaflet prolapse present unique surgical challenges.
Observation:
- Intraoperative findings revealed a 13x7 mm perforation of the anterior mitral leaflet (AML) and prolapse of the posterior mitral leaflet (PML).
- A novel surgical approach involved resecting a portion of the PML and utilizing it as a patch to cover the AML perforation.
Findings:
- The resected PML segment was successfully used to repair the AML perforation.
- A Carpentier-Edwards rigid ring (30 mm) was implanted to stabilize the mitral annulus.
- The patient experienced an uneventful recovery with no residual mitral regurgitation on postoperative echocardiography.
Implications:
- This technique offers a viable solution for complex mitral valve pathologies involving leaflet perforation.
- Successful valve repair can prevent the need for valve replacement, preserving native valve function.
- The described surgical strategy may improve outcomes for patients with severe MR due to leaflet defects.
Related Concept Videos
Mitral Valve Prolapse III: Nursing Management
Mitral Regurgitation III: Medical Management
Mitral Stenosis I: Introduction
Mitral Stenosis III: Medical Management
Endocarditis I: Introduction
Endocarditis III: Medical Management

