Related Experiment Video
Updated: Aug 11, 2026

An Unpredictable Chronic Mild Stress Protocol for Instigating Depressive Symptoms, Behavioral Changes and Negative Health Outcomes in Rodents
Published on: December 2, 2015
[Major depressive disorders and psychiatric emergencies: a naturalistic study on crisis intervention relevance]
Cristian Damsa1, Coralie Lazignac, Lionel Cailhol
1Service d'accueil, d'urgences et de liaison psychiatrique, Hôpital Cantonal Universitaire de Genève, Suisse. c.damsa@bluewin.ch
Objective:
This retrospective study aimed to evaluate the impact of introducing crisis intervention patterns in the emergency unit of a general hospital on the number of admissions and outpatient follow-ups for patients with major depressive disorder.
Method:
The study included all patients with major depressive disorder (DSM-IV criteria) who visited the psychiatric emergency unit in a general hospital during two 8-month periods: before (425 patients) and after (436 patients) crisis interventions were introduced.
Results:
After crisis interventions were introduced, the voluntary admission rate decreased significantly (from 17.9% to 12.4%), while the number of outpatient follow-ups increased (from 82.1% to 86.2%). Borderline personality disorder was associated with a significant reduction of the admission rate (27.8% against 38.2%), while the admission rate for patients with depressive disorder with psychotic features did not decline after crisis interventions. Crisis interventions were more effective on women.
Conclusions:
These outcomes suggest the relevance of crisis intervention in psychiatric emergency settings to improve the management of patients with major depressive disorder. Crisis intervention fosters outpatient multimodal follow-up rather than admission in a psychiatric setting.
Related Concept Videos
Depressive Disorders: Etiology
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Depression: Overview
Community Based Intervention
Foundations of Community Mental Health Programs
Central to the success of community-based interventions is the...
Introduction to Stress and Lifestyle
Panic Disorder
Stress and Mental Health
Individuals with depression often experience challenges in both their personal and professional...