Related Experiment Video
Updated: Aug 11, 2026

Isolation of Sertoli Cells and Peritubular Cells from Rat Testes
Published on: February 8, 2016
[Relationship between insulin like hormone 3 and testicular descent and development]
1Department of Pediatric Surgery, the Second Hospital of Shantou University Medical College, Shantou, Guangdong 515041, China. xiexiaojun11908@tom.com
Abstract:
Testicular descent is an essential step in the course of reproductive system development. The mechanisms involved in the regulation of testis descent is not distinct. Gubernaculum has a very close relationship with testis descent. Maldescent of testis can cause abnormalities of genital system such as testicular underwent (cryptorchidism), dysplasia, tumor, infertility and low sexuality. Recently insulin like hormone 3 is a hotspot of concerning affecting gubernacular development and testicular descent. This article briefly reviews the advances in these aspects.
Related Concept Videos
Testosterone: Functions and Regulation
Development of the Sexual Organs in the Embryo and Fetus
Near the gonadal ridges, two duct systems are present: the mesonephric ducts (Wolffian ducts) and paramesonephric ducts (Müllerian ducts). These ducts form the basis for the male...
Insulin: The Receptor and Signaling Pathways
Gonadal and Placental Hormones
In males, testosterone is the primary gonadal androgen. It plays a central role in the maturation of male reproductive organs — the penis and testes. Additionally, testosterone is instrumental in the development of secondary sexual characteristics — a deep voice as well as facial and pubic hair growth — and...
Testes: Histology
The spermatogenic cells, responsible for producing sperm, are...
The Endocrine System

