Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Fluid resuscitation in major burns.

Biswadev Mitra1, Mark Fitzgerald, Peter Cameron

  • 1The Alfred Emergency and Trauma Centre, Prahran, Victoria 3181, Australia. tamponade@bigpond.com

ANZ Journal of Surgery
|February 18, 2006
PubMed
Summary

Major burn patients received significantly more fluid resuscitation than the Parkland formula suggests, without adverse effects. This finding supports further research into revised fluid resuscitation guidelines for major burns.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Consensus statements for the diagnosis of mild traumatic brain injury and clinical integration of blood-based biomarkers in the Asia-Pacific region: a modified Delphi study.

International journal of emergency medicine·2026
Same author

From single to dual platelet inhibition FIBTEM assay: fibrinogen replacement thresholds for critical bleeding after trauma.

European journal of trauma and emergency surgery : official publication of the European Trauma Society·2026
Same author

Repeated traumatic brain injury in civilian emergency care: An exploration of potential risk factors.

Clinical neurology and neurosurgery·2026
Same author

Response to 'The Sedation Gap Conundrum: Where's the Awareness?'

Emergency medicine Australasia : EMA·2026
Same author

Review of paediatric deaths in the emergency department provides important considerations for an uncommon, but distressing event.

Evidence-based nursing·2026
Same author

Diagnostic Accuracy of Plasma Biomarkers for Mild Traumatic Brain Injury in Older Adults.

JAMA network open·2026

Area of Science:

  • Burn care and trauma management
  • Critical care medicine
  • Emergency medicine

Background:

  • The Parkland formula is the standard for initial fluid resuscitation in major burns.
  • Anecdotal evidence suggested significant deviations from the Parkland formula in practice.
  • This study aimed to investigate these variations and their potential impact.

Purpose of the Study:

  • To review fluid resuscitation practices for major burns at The Alfred Burns Unit.
  • To determine the prevalence of deviations from the Parkland formula.
  • To assess if these deviations could inform revisions to fluid resuscitation protocols.

Main Methods:

  • Retrospective review of 127 major burn presentations (TBSA ≥15%).
  • Analysis of resuscitation data for 49 patients with complete and uncomplicated burn information.

Related Experiment Videos

  • Comparison of administered fluid volumes against the Parkland formula predictions.

    • Main Results:

    • Patients received significantly higher fluid volumes (5.58 mL/kg/%TBSA) in the first 24 hours than predicted by the Parkland formula.
    • Mean arterial pressure, pulse rate, and urine output remained within satisfactory ranges.
    • Minimal clinically evident complications from fluid administration were observed, with mortality rates comparable to other centers.

    Conclusions:

    • Higher fluid resuscitation volumes than the Parkland formula, when administered, did not result in adverse consequences.
    • This retrospective data supports the need for a prospective study comparing current practices with the Parkland formula.
    • Such a study could lead to improved guidelines for initial fluid resuscitation in major burn patients.