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Recurrent acute profound thrombocytopenia related to readministration of eptifibatide

Aamir Adnan Cheema1, Andrew Henry Teklinski, Viqar Maria

  • 1Department of Internal Medicine, Division of Cardiology, St. John Hospital and Medical Center, Detroit, MI 48236, USA. acheema75@yahoo.com

Journal of Interventional Cardiology
|February 18, 2006
PubMed

We describe the case of an 86-year-old woman who presented with unstable angina. She was given heparin and eptifibatide, and she underwent percutaneous coronary intervention (PCI). Shortly thereafter, she developed acute profound thrombocytopenia (6,000 platelets/mm3), which resolved after the discontinuation of heparin and eptifibatide. Four months later, she presented again with unstable angina and underwent PCI. Soon after the procedure, she again developed acute profound thrombocytopenia (2,000 platelets/mm3). To our knowledge, acute profound thrombocytopenia due to eptifibatide treatment in the same patient at two different times has not been reported before.

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