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Updated: Jul 28, 2026

Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis
Published on: July 19, 2018
Why bury the distal end of the peritoneal dialysis catheter
1Jack Moncrief Group and Moncrief Dialysis Center, Austin, TX 78705, USA. jbmoncrief@msn.com
Abstract:
The first catheters for peritoneal dialysis were made in silicone with a Dacron cuff, which allowed tissue ingrowth, creating a barrier to the entrance of bacteria from the skin surface. However, the interruption of the skin envelope produces recurrent exit site and tunnel infections and peritonitis, which are the leading causes of discontinuing peritoneal dialysis. Experimental evidence suggests that the use of a double cuff silastic catheter and subcutaneous implantation of the distal catheter for 5-6 weeks before exposure reduces such infections, thus improving catheter life. Early preparation of peritoneal dialysis access with subcutaneous implantation allows healing of scar tissue into the cuffs and formation of an excellent bacteriological barrier.
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