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Updated: Aug 11, 2026

Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice
Published on: June 28, 2021
[Recurrent acute pancreatitis during pravastatin-therapy]
C Becker1, C Hvalic, G Delmore
1Klinische Pharmakologie und Toxikologie, Universitätsspital Basel. beckerc@uhbs.ch
Abstract:
Acute pancreatitis can rarely be caused also by drugs. Several substances from different drug classes have been associated with the occurrence of acute pancreatitis. Regarding the class of the hydroxymethylglutaryl-CoA-reductase-inhibitors (statins) case-reports have been published in the literature in association with each individual statin. We present a 60-years-old male who developed twice an acute pancreatitis while being treated with pravastatin. Because some case reports describe the reoccurrence of acute pancreatitis after exposure to a different statin, recommendations for further therapy remain complex. There are also case reports of pancreatitis associated with fibrates and information on rare adverse reactions associated with ezetimibe is sparse.
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