Ethnic differences in the distribution of interleukin-6 polymorphisms among three Brazilian ethnic groups
S R Gadelha1, L C Alcantara, G C S Costa
1Laboratório Avançado de Saúde Pública, Centro de Pesquisas Gonçalo Moniz, Fundação Oswaldo Cruz, rua Waldemar Falcão 121, Salvador, Brazil.
Human Biology
|February 21, 2006
Abstract:
Polymorphisms in the interleukin-6 promoter region have been associated with diseases. In this study we investigated the -634G/C and -174G/C IL-6 promoter polymorphisms in three Brazilian ethnic groups. We verified that the allele frequencies of the two polymorphisms and haplotype frequencies varied significantly between the populations.
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