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A Modified Two Kidney One Clip Mouse Model of Renin Regulation in Renal Artery Stenosis
Published on: October 26, 2020
Renal artery stenosis: today's questions
Thomas K A Wierema1, Peter W de Leeuw
1Department of Internal Medicine, University Hospital Maastricht, PO Box 5800, 6202 AZ Maastricht, The Netherlands. twie@sint.azm.nl
Abstract:
Renal artery stenosis remains a challenge, not only in terms of diagnosis but also in regard to when and how to treat this disease. Diagnostic tools that seemed promising have been unmasked as unreliable, and new treatment options such as angioplasty have failed to demonstrate their superiority. In the light of these disappointments, the most fundamental question appears to be: when is a stenosis relevant and therefore clinically significant, and how to proceed from there?
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